pmcJAMA Netw OpenJAMA Netw Open3211jamasd101729235JAMA Network Open2574-3805pmc-is-collection-domainyespmc-collection-titleJAMA NetworkPMC13543018PMC13543018.113543018135430184269066110.1001/jamanetworkopen.2026.32033zld2601831ResearchResearch LetterOnline OnlyCommentsHealth InformaticsArtificial Intelligence–Generated Discharge Dates and Estimation Accuracy in Hospitalized PatientsAI-Generated Hospital Discharge Dates and Estimation AccuracyAI-Generated Hospital Discharge Dates and Estimation AccuracyKanthetiHavish S.MD 1 DolanConnorBS 1 DaleJordanMD 2 Texas A&M School of Engineering Medicine, HoustonDepartment of Medicine, Houston Methodist Hospital, Houston, TexasArticle Information

Accepted for Publication: July 7, 2026.

Published: September 3, 2026. doi:10.1001/jamanetworkopen.2026.32033

Open Access: This is an open access article distributed under the terms of the CC-BY-NC-ND License, which does not permit alteration or commercial use, including those for text and data mining, AI training, and similar technologies. © 2026 Kantheti HS et al. JAMA Network Open.

Corresponding Author: Jordan Dale, MD, Department of Medicine, Houston Methodist Hospital, 6565 Fannin St, Houston, TX 77030 (jordan.dale@houstonmethodist.org).

Author Contributions: Drs Kantheti and Dale had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

Concept and design: All authors.

Acquisition, analysis, or interpretation of data: Kantheti, Dale.

Drafting of the manuscript: All authors.

Critical review of the manuscript for important intellectual content: Kantheti, Dale.

Statistical analysis: Kantheti.

Administrative, technical, or material support: Dale.

Supervision: Dale.

Conflict of Interest Disclosures: None reported.

Funding/Support: This study was supported by institutional and departmental resources.

Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.

Data Sharing Statement: See Supplement 2.

3920269202699520944e2632033942026772026030920260509202605092026Copyright 2026 Kantheti HS et al. JAMA Network Open.2026Kantheti HS et alhttps://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the CC-BY-NC-ND License, which does not permit alteration or commercial use, including those for text and data mining, AI training, and similar technologies.jamanetwopen-e2632033.pdf

This quality improvement study compares true hospital discharge dates with those estimated using artificial intelligence (AI) and by case managers.

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Introduction

Accurate estimation of a hospitalized patient’s discharge date supports bed planning, throughput, and postacute care coordination. Machine learning applied to electronic health record (EHR) data can generate expected discharge dates,1,2,3 and commercial tools are increasingly used in practice.2,4 Most evaluations, however, benchmark a tool against the true discharge date in isolation rather than against the prevailing standard of care—the case manager’s estimate.5 We compared the accuracy of an artificial intelligence (AI)–generated discharge date with contemporaneous, independently generated case manager estimates and both estimates with the true discharge date across the hospital course.

Methods

This quality improvement study included inpatient encounters at Houston Methodist Hospital with discharge dates between August 1, 2023, and February 28, 2024. The hospital’s institutional review board determined the study exempt from review with a waiver of informed consent as data were deidentified. The study followed the SQUIRE reporting guideline. No baseline patient demographic data were available.

Artificial intelligence–estimated discharge dates were generated by a commercial clinician-assisted tool integrated with the EHR. Case manager–expected discharge dates were recorded during usual care in a workflow independent of the AI tool. Both were compared with the true discharge date from the EHR. The tool returned either an exact date or a categorical estimate; nonexact values were excluded, and 2.6% of encounters had no exact AI estimation (eMethods in Supplement 1).

We assessed estimations at 3 time points: admission (first available estimate per method) and 48 and 24 hours before discharge (first estimate in a symmetric window 36-60 and 12-36 hours before true discharge, applied identically to both methods). Accuracy was quantified as mean absolute error (MAE) and systematic bias as the mean signed difference (estimated minus true date), each with 95% CIs. Paired t tests compared methods (2-sided α = .05). Agreement was assessed using Bland-Altman analysis; Pearson correlation did not capture systematic bias between methods. Prespecified subgroup (length of stay [LOS], unit type) and sensitivity analyses were performed. Analyses were performed using R, version 4.3.3 (R Foundation for Statistical Computing) and Python, version 3.12.2 (Python Software Foundation).

Results

A total of 22 349 inpatient encounters among 17 173 patients had both AI- and case manager–estimated discharge dates. The number per comparison varied by time point, since the near-discharge analyses required an in-window estimation (admission, n = 21 710; 48 hours, n = 9236; 24 hours, n = 12 172). Median (IQR) LOS was 5 (3-8) days. At admission, accuracy was similar between methods (MAE, 4.20 [95% CI, 4.08-4.31] vs 4.27 [4.15-4.38] days; P = .001), although case managers matched the exact date more often (23.6% vs 15.3%) and fell within 1 day more often (46.3% vs 40.8%). Nearer to discharge, case managers vs AI were more accurate (48 hours: MAE, 1.29 [95% CI, 1.26-1.32] vs 1.59 [95% CI 1.57-1.61] days; 24 hours: MAE, 0.98 [95% CI, 0.96-1.01] vs 1.93 [95% CI, 1.91-1.95] days) (both P < .001). At 24 hours, 79.5% of case manager estimations fell within 1 day vs 37.9% for AI estimations (Table; Figure).

Discharge Date Estimation Accuracy and Agreement: AI vs Case Manager<xref rid="zld260183t1n1" ref-type="table-fn"><sup>a</sup></xref>
MeasureAdmission (n = 21 710)a48 h before discharge (n = 9236)b24 h before discharge (n = 12 172)b
AICase managerAICase managerAICase manager
MAE (95% CI), dc4.20 (4.08 to 4.31)4.27 (4.15 to 4.38)1.59 (1.57 to 1.61)1.29 (1.26 to 1.32)1.93 (1.91 to 1.95)0.98 (0.96 to 1.01)
Mean difference (95% CI), dc,d−2.74 (−2.86 to −2.62)−3.40 (−3.53 to −3.28)0.50 (0.47 to 0.54)−0.68 (−0.72 to −0.64)1.24 (1.21 to 1.28)0.04 (0.01 to 0.07)
Within 1 d, No. (%)8858 (40.8)10 050 (46.3)3852 (41.7)5875 (63.6)4608 (37.9)9681 (79.5)
Exact match, No. (%)e3319 (15.3)5115 (23.6)1257 (13.6)2284 (24.7)945 (7.8)4089 (33.6)

Abbreviations: AI, artificial intelligence; LOA, limit of agreement; MAE, mean absolute error.

Subgroup, case manager–level, and single-encounter sensitivity results are described in the text.

Bland-Altman bias (the mean of AI minus case manager) differences were 0.67 days (95% LOA, −6.39 to 7.72 days) for admissions, 1.18 days (95% LOA, −3.39 to 5.76 days) for 48 hours before discharge, and 1.21 days (−3.50 to 5.91 days) for 24 hours before discharge.

P < .001 for all MAE and mean difference comparisons except admission MAE (P = .001).

Mean difference is estimated minus true discharge date (negative sign indicates underestimation).

Exact match rates were as follows for AI vs case manager: admission, 15.3% vs 23.6%; 24 h, 7.8% vs 33.6%.

Bar Graphs and Bland-Altman Plot of Artificial Intelligence (AI) vs Case Manager Discharge Date Estimation Accuracy Across Time Points

A, Error bars indicate 95% CIs. C, The solid line indicates the mean bias (AI minus case manager), and the dashed lines indicate the 95% limits of agreement.

Three-panel figure: two bar charts and one Bland-Altman scatter plot.Panel A titled Accuracy. Grouped vertical bar chart with horizontal axis labeled Time before discharge, h, with categories Admission, 48, and 24. Vertical axis labeled Mean absolute error, d, ranging from 0 to 5. Two series: A I in blue gray and Case manager in orange, with small black error bars. At Admission, both bars near 4.2 to 4.3 days. At 48, A I near 1.6 days and Case manager near 1.3 days. At 24, A I near 1.9 days and Case manager near 1.0 day. Panel B titled Within-1-d accuracy. Grouped vertical bar chart with the same three time categories on the horizontal axis. Vertical axis labeled Estimates within 1 day, percent, ranging from 0 to 100. A I bars near 41 percent at Admission, 42 percent at 48, and 38 percent at 24. Case manager bars near 46 percent at Admission, 64 percent at 48, and 80 percent at 24. A legend near the top labels the blue gray series as A I and the orange series as Case manager. Panel C titled Bland-Altman, 24 h. Scatter plot of hexagon markers colored by density with a vertical color bar at right labeled Encounters, No. ranging from about 200 to 1000 plus, light to dark blue. Horizontal axis labeled Mean of A I and case manager error, d, ranging from about minus 4 to 8. Vertical axis labeled A I minus case manager, d, ranging from minus 8 to 8. A solid horizontal line at about 1.2 days and two dashed horizontal lines near about 6.0 and minus 3.5 days. Text at the top reads Bias (95% LoA) equals 1.21 (3.50-5.91).

Signed differences showed AI shifting from underestimating LOS at admission (mean difference, −2.74 [95% CI, −2.86 to −2.62] days) to overestimating it near discharge (mean difference, 1.24 [95% CI, 1.21-1.28] days at 24 hours), whereas case manager estimates remained close to the true date throughout (mean difference, −3.4 [95% CI, −3.53 to −3.28] and 0.04 [95% CI, 0.01-0.07] days, respectively). The 2 methods correlated strongly at admission (r = 0.92) but weakly nearer discharge (r = 0.12). Bland-Altman analysis showed a positive bias favoring later AI estimation, with wide limits of agreement at every time point (Table).

In subgroup analysis, relative accuracy varied by LOS, with AI less accurate than case managers for very short stays (1-2 days: MAE, 1.66 [95% CI, 1.62-1.70] vs 0.89 [95% CI, 0.84-0.94] days) but more accurate for intermediate stays (5-7 days: MAE, 1.49 [95% CI, 1.46-1.53] vs 2.24 [95% CI, 2.19-2.29] days), with both performing poorly beyond 14 days. Case managers were substantially more accurate on the obstetric unit, and both methods performed poorly in the intensive care unit. Accuracy varied widely across individual case managers. Restricting to 1 encounter per patient did not change the admission comparison.

Discussion

This quality improvement study found that AI-estimated discharge was comparable to usual care at admission but outperformed by case managers as discharge approached (when accurate estimations are most actionable for bed management). The strong admission correlation did not persist nearer discharge and should not be interpreted as evidence that the tool captured the same information clinicians use throughout the stay. Any benefit seemed concentrated in intermediate-stay patients rather than uniform.

Several limitations apply. This single-center analysis assessed estimation accuracy, not downstream clinical decisions or patient outcomes; thus, the findings are hypothesis-generating. Case manager estimates were part of usual care and visible to care teams, so they may be partly self-fulfilling and, thus, advantaged nearer discharge; AI estimations were accessible in the EHR but not enabled automatically. Case management practices were not standardized, and performance varied across case managers. Whether the AI’s incremental accuracy in selected subgroups justifies the complexity of implementation warrants prospective, outcome-based evaluation.

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eMethods.

Data Sharing Statement